Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /www/wp-content/plugins/revslider/includes/operations.class.php on line 2758 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /www/wp-content/plugins/revslider/includes/operations.class.php on line 2762 Warning: "continue" targeting switch is equivalent to "break". Did you mean to use "continue 2"? in /www/wp-content/plugins/revslider/includes/output.class.php on line 3706 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Function get_magic_quotes_gpc() is deprecated in /www/wp-content/plugins/wordfence/vendor/wordfence/wf-waf/src/lib/utils.php on line 354 Deprecated: Array and string offset access syntax with curly braces is deprecated in /www/wp-content/plugins/wordfence/lib/Diff/Renderer/Html/Array.php on line 153 Deprecated: Array and string offset access syntax with curly braces is deprecated in /www/wp-content/plugins/wordfence/lib/Diff/Renderer/Html/Array.php on line 153 What Causes UC? | National Ulcerative Colitis Alliance What Causes UC? | National Ulcerative Colitis Alliance Deprecated: wp_make_content_images_responsive is deprecated since version 5.5.0! Use wp_filter_content_tags() instead. in /www/wp-includes/functions.php on line 4777 Deprecated: wp_make_content_images_responsive is deprecated since version 5.5.0! Use wp_filter_content_tags() instead. in /www/wp-includes/functions.php on line 4777

The National Ulcerative Colitis Alliance (NUCA) is a qualified 501(c)(3) tax-exempt organization.

Deprecated: wp_make_content_images_responsive is deprecated since version 5.5.0! Use wp_filter_content_tags() instead. in /www/wp-includes/functions.php on line 4777

What Causes Ulcerative Colitis?

The exact cause of ulcerative colitis (UC) is unknown. Researchers believe the following factors may play a role in causing UC:

  • Overactive intestinal immune system
  • Genes
  • Environment

Overactive Intestinal Immune System


One cause of UC may be an abnormal immune reaction in the intestine. Normally, the immune system protects the body from infection by identifying and destroying bacteria, viruses, and other potentially harmful foreign substances. Bacteria or viruses may mistakenly trigger the immune system to attack the inner lining of the large intestine. This immune system response causes inflammation, leading to symptoms.

Genes


Ulcerative colitis sometimes runs in families. Studies have shown that certain abnormal genes may appear in people with UC. However, researchers have not been able to show a clear link between the abnormal genes and UC.

Environment


Some studies suggest that certain things in the environment may increase the chance of a person developing UC, although the overall chance is low. Nonsteroidal anti-inflammatory drugs, antibiotics, and oral contraceptives may slightly increase the chance of developing UC. A high-fat diet may also slightly increase the chance of developing UC.

Some people believe eating certain foods, stress, or emotional distress can cause UC. Emotional distress does not seem to cause UC; however, a few studies suggest that stress may increase a person's chance of having a flare-up of UC. Also, some people may find that certain foods can trigger or worsen symptoms.

Reference:

The National Institute of Diabetes and Digestive and Kidney Diseases. Ulcerative colitis. https://www.niddk.nih.gov/health-information/digestive-diseases/ulcerative-colitis. Accessed February 14, 2018.