The National Ulcerative Colitis Alliance (NUCA) is a qualified 501(c)(3) tax-exempt organization.

Signs & Symptoms of Ulcerative Colitis

The most common signs and symptoms of ulcerative colitis (UC) are diarrhea with blood or pus and abdominal discomfort.

Other signs and symptoms include

  • Urgent need to have a bowel movement
  • Feeling tired
  • Nausea or loss of appetite
  • Weight loss
  • Fever
  • Anemia—a condition in which the body has fewer red blood cells than normal

Less common symptoms include

  • Joint pain or soreness
  • Eye irritation
  • Certain rashes

The symptoms a person experiences can vary depending on the severity of the inflammation and where it occurs in the intestine. When symptoms first appear,

  • Most people with UC have mild to moderate symptoms
  • About 10% of people can have severe symptoms, such as frequent, bloody bowel movements; fevers; and severe abdominal cramping


The National Institute of Diabetes and Digestive and Kidney Diseases. Ulcerative colitis. Accessed February 14, 2018.