The National Ulcerative Colitis Alliance (NUCA) is a qualified 501(c)(3) tax-exempt organization.

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About UC

Ulcerative colitis (UC) is a lifelong, chronic disease that primarily affects the lining of the large intestine by causing ulcers (sores).

Did UC? Blog

NUCA's blog "Did UC?" features stories from the community, upcoming events, and other helpful information for people living with UC.


About UC

Signs & Symptoms

The signs and symptoms of UC are similar to other conditions, making diagnosis a challenge.

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Management & Prognosis

Management of UC may include receiving care from a digestive specialist, various medications, and in some cases, surgery.

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Causes of UC

Scientists don’t know exactly what causes UC, but there are some strong working theories.

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Treating UC

When treating UC, there are medical and surgical options to consider.

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Diagnosing UC

UC is often diagnosed by a gastroenterologist through a combination of medical history and diagnostic tests.

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Your Care Team

UC can affect the entire body, which means engaging the help of a multidisciplinary care team.

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Join the NUCA Community

For those living with UC and the people in their lives, NUCA strives to improve current quality of life through education, support, community connections, and empowerment. Click the button below to join the NUCA community.


The National Institute of Diabetes and Digestive and Kidney Diseases. Ulcerative colitis. Accessed February 14, 2018.